TUHH> ITB

Institute of Technical Biocatalysis

Publications of Prof. Andreas Liese


TypeYear
Publications in journals 2016, 2015, 2014, 2013, 2012, 2011, 2010, 20092008, 2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999
Books - 2012
Book chapters - 2012
Other publications - 2012
Patents - 2012
Patent applications - 2012

Publications in journals

2016

  • G. S. Molla, R. Wohlgemuth, A. Liese
    One-pot enzymatic reaction sequence for the syntheses of d-glyceraldehyde 3-phosphate and l-glycerol 3-phosphate
    Journal of Molecular Catalysis B: Enzymatic, 124 (2016) 77-82
    DOI: 10.1016/j.molcatb.2015.12.004
  • S. K. Gaßmeyer, J. Wetzig, C. Mügge, M. Assmann, J. Enoki, L. Hilterhaus, R. Zuhse, K. Miyamoto, R. Kourist, A. Liese
    Arylmalonate Decarboxylase-Catalyzed Asymmetric Synthesis of Both Enantiomers of Optically Pure Flurbiprofen
    ChemCatChem, 8, 916-921 (2016)
    DOI: 10.1002/cctc.201501205

2015

  • L. Pesci, S. Glück, P. Gurikov, I. Smirnova, K. Faber, A. Liese
    Biocatalytic Carboxylation of Phenol Derivatives: Kinetics and Thermodynamics of the Biological Kolbe-Schmitt Synthesis
    FEBS Journal 282 (2015) 1334-1345
    DOI: 10.1111/febs.13225
  • R. Heils, J.-H. Jensen, S. Wichert, N. Behrens, M. Fabuel-Ortega, A. Liese, I. Smirnova
    Enzymatic Reactive Distillation: Kinetic Resolution of rac-2-Pentanol with Biocatalytic Coatings on Structured Packings
    Ind. Eng. Chem. Res. 54 (38) (2015) 9458–9467
    DOI: 10.1021/acs.iecr.5b02802
  • S. Schmidt, H. C. Büchsenschütz, C. Scherkus, A. Liese, H. Gröger, U. T. Bornscheuer
    Biocatalytic Access to Chiral Polyesters by an Artificial Enzyme Cascade Synthesis
    ChemCatChem 7 (2015) 3951-3955
    DOI: 10.1002/cctc.201500823
  • M. Berheide, S. Kara, A. Liese
    Reversibility of Asymmetric Catalyzed C–C Bond Formation by Benzoylformate Decarboxylase
    Catalysis Science & Technology (2015)
    5 (2015) 2418-2426 DOI: 10.1039/C4CY00171K
  • M. Pöhnlein, J. Ulrich, F. Kirschhöfer, M. Nusser, C. Muhle-Goll, B. Kannengiesser, G. Brenner-Weiß, B. Luy, A. Liese, C. Syldatk, R. Hausmann
    Lipase-catalyzed synthesis of glucose-6-O-hexanoate in deep eutectic solvents
    European Journal of Lipid Science and Technology
    117 (2) (2015) 161-166 DOI: 10.1002/ejlt.201400459
  • S. Schmidt, C. Scherkus, J. Muschiol, U. Menyes, T. Winkler, W. Hummel, H. Gröger, A. Liese, H.-G. Herz, U. T. Bornscheuer
    An Enzyme Cascade Synthesis of Oligo-ε-Caprolactone
    Angewandte Chemie Int. Ed.
    54 (2015) 1-5 DOI: 10.1002/anie.201410633

2014

  • G. S. Molla, P. J. Venkatesh, A. Liese
    Single-Pot Enzymatic Reaction Sequence for the Synthesis of D -Glyceraldehyde-3-Phosphate
    Chemie Ingenieur Technik, 86 (9) (2014), 1424
    DOI: 10.1002/cite.201450599
  • D. Kaufhold, J. Fagaschewski, D. Sellin, S. Strompen, A. Liese, L. Hilterhaus
    Novel µ-Membrane Module for the Online Determination of the Free Fatty Acid Content in the Dispersed Phase of oil in water Emulsions
    Analytical and Bioanalytical Chemistry (2014) 406 (13) 3157-66
    DOI: 10.1007/s00216-014-7740-9
  • J. M. Kisch, C. Utpatel, L. Hilterhaus, W. R. Streit, A. Liese
    Pseudomonas aeruginosa Biofilm Growth Inhibition on Medical Plastic Materials by Immobilized Esterases and Acylase
    ChemBioChem (online) (2014)
    DOI: 10.1002/cbic.201400023
  • C. Scherkus, A. Liese, H. Gröger, U. Kragl, U. Bornscheuer, U. Menyes
    Prozessentwicklung zur enzymatischen Synthese eines biologisch abbaubaren Polymers
    Chemie Ingenieur Technik (2014)
    86 (9) (2014) 1424-1425 DOI: 10.1002/cite.201450586
  • S. Baum, M. Schilling, D. Sellin, A. Liese
    Steuerung der Reaktionsselektivität von Biotransformationen mittels Online-FTIR-Analytik
    Chemie Ingenieur Technik (2014)
    86 (9) (2014) 1583-1584 DOI: 10.1002/cite.201450600
  • F. Rieckenberg, K. Götz, L. Hilterhaus, A. Liese, A.-P. Zeng
    Strategies for reliable and improved large-scale production of Pyrococcus furiosus with integrated purification of hydrogenase I
    Bioprocess Biosyst Eng.
    37 (12) (2014) 2475-82 DOI: 10.1007/s00449-014-1225-2

2013

  • S. Cumana, J. Simons, A. Liese, L. Hilterhaus, I. Smirnova
    Immobilization of glucose 6-phosphate dehydrogenase in silica-based hydrogels: a comparative study
    Journal of Molecular Catalysis B: Enzymatic 85–86 (2013) 220-228
    DOI: 10.1016j.molcatb.2012.09.014
  • K. Götz, A. Liese, M. Ansorge-Schumacher, L. Hilterhaus
    A chemo-enzymatic route to synthesize (S)-gamma-valerolactone from levulinic acid
    Appl Microbiol Biotechnol 97 (9) (2013) 3865-3873
    DOI: 10.1007/s00253-012-4652-5
  • D. Kaufhold, F. Kopf, C. Wolff, S. Beutel, L. Hilterhaus, M. Hoffmann, T. Scheper, M. Schlüter, A. Liese
    Reaktive Absorption von Kohlenstoffdioxid in helikalen Hohlfasermembrankontaktoren
    Chemie Ingenieur Technik, 85 (4) (2013) 476-483
    DOI: 10.1002/cite.201200240
  • A. Liese, L. Hilterhaus
    Evaluation of immobilized enzymes for industrial applications
    Chemical Society Reviews, 42 (2013) 6236-6249
    DOI: 10.1039/C3CS35511J
  • J. Gebhard, D. Sellin, L. Hilterhaus, A. Liese
    Online-Analyse von enzymatischen Polykondensationsreaktionen in Blasensäulenreaktoren mittels ATR-FTIR Spektroskopie
    Chemie Ingenieur Technik, 85 (4) (2013) 1-8
    DOI: 10.1002/cite.201200248
  • A. Liese, U. Kragl
    Einfluss der Reaktorkonfiguration auf die Enantioselektivität einer kinetischen Racematspaltung
    Chemie Ingenieur Technik, 85 (6) (2013) 826-832
    DOI: 10.1002/cite.201300011
  • A. Liese
    Die Zukunft liegt in der interdisziplinären Forschung und Entwicklung
    Chemie Ingenieur Technik, 85 (6) (2013) 771
    DOI: 10.1002/cite.201390047
  • S. Strompen, M. Weiß, H. Gröger, L. Hilterhaus, A. Liese
    Development of a continuously operating process for the enantioselective synthesis of a beta-amino acid ester via a solvent-free chemoenzymatic reaction sequence
    Advanced Synthesis Catalysis 355 (11-12) (2013) 2391-2399
    DOI: 10.1002/adsc.201300236
  • B. Opitz, A. Prediger, C. Luder, M. Eckstein, L. Hilterhaus, P. Lindner, S. Beutel, T. Scheper, A. Liese
    In Situ Microscopy for In-line Monitoring of the Enzymatic Hydrolysis
    Analytical Chemistry 85 (17) (2013) 8121-8126
    DOI: 10.1021/ac4008495

2012

  • J. Chow, F. Kovacic, Y. Dall Antonia, U. Krauss, F. Fersini, C. Schmeisser, B. Lauinger, P. Bongen, J. Pietruszka, M. Schmidt, I. Menyes, U. T. Bornscheuer, M. Eckstein, O. Thum, A. Liese, J. Mueller-Dieckmann, K.-E. Jaeger, W. R. Streit
    The Metagenome-Derived Enzymes LipS and LipT Increase the Diversity of Known Lipases
    PLOS ONE 7 (10) (2012) e47665
    DOI:10.1371/journal.pone.0047665
  • R. Heils, A. Sont, P. Bubenheim, A. Liese, I. Smirnova
    Integration of enzymatic catalysts in a reactive distillation column with structured packings
    Industrial & Engineering Chemistry Research, 51 (35) (2012) 11482–11489
    DOI: 10.1021/ie300837v
  • K. T. Schomburg, I. Ardao, K. Götz, F. Rieckenberg, A. Liese, A.-P. Zeng, M. Rarey
    Computational Biotechnology: Prediction of competitive substrate inhibition of enzymes by buffer compounds with protein-ligand docking
    Journal of Biotechnology 161 (2012) 391-401
    DOI: 10.1016/j.jbiotec.2012.08.002
  • D. Kaufhold, F. Kopf, C. Wolff, S. Beutel, L. Hilterhaus, M. Hoffmann, T. Scheper, M. Schlüter, A. Liese
    Generation of Dean vortices and enhancement of oxygen transfer rates in membrane contactors for different hollow fiber geometries
    Journal of Membrane Science 423-424 (2012) 342-347
    DOI: 10.1016/j.memsci.2012.08.035
  • S. Strompen, M. Weiss, T. Ingram, I. Smirnova, H. Gröger, L. Hilterhaus, A. Liese
    Kinetic investigation of a solvent-free, chemoenzymatic reaction sequence towards enantioselective synthesis of a β-amino acid ester
    Biotechnology and Bioengineering 109 (6) (2012) 1479–1489
    DOI: 10.1002/bit.24422
  • S. Cumana, J. Simons, A. Liese, L. Hilterhaus, I. Smirnova
    Immobilization of glucose 6-phosphate dehydrogenase in silica-based hydrogels: a comparative study
    Journal of Molecular Catalysis B: Enzymatic 85–86 (2013) 220-228
    http://dx.doi.org/10.1016/j.molcatb.2012.09.014

2011

  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ Mikroskopie zur online-Überwachung von enzymatischen Prozessen
    Chemie Ingenieur Technik 83 (5) (2011) 1-5, DOI: 10.1002/cite.201000203
  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ microscopy for online monitoring of enzyme carriers and two-phase processes
    Chemical Engineering & Technology 34 (5) (2011) 837-840,
    DOI: 10.1002/ceat.201000563
  • S. Kara, W. S. Long, M. Berheide, S. Peper, B. Niemeyer, A. Liese
    Influence of reaction conditions on the enantioselectivity of biocatalyzed C–C bond formations under high pressure conditions
    Journal of Biotechnology 152 (3) 87-92, DOI: 10.1016/j.jbiotec.2011.01.020
  • S. Peper, S. Kara, W. S. Long, A. Liese, B. Niemeyer
    Immobilization and characterization of benzoylformatedecarboxylase from Pseudomonas putida on sphericalsilica carrier
    Bioprocess Biosyst Eng, 34 (6) (2011) 671-680, DOI: 10.1007/s00449-011-0516-0
  • S. Kara, J. Müller, A. Liese
    Online analysis methods for monitoring of bioprocesses
    Chemistry Today 29 (2) (2011) 38-41
  • J. Brummund, F. Meyer, A. Liese, R. Eggers, L. Hilterhaus
    Dissolving carbon dioxide in high viscous substrates to accelerate biocatalytic reactions
    Biotechnology & Bioengineering (2011) 108 (11) (2011) 2765-2769, DOI: 10.1002/bit.23230
  • F. Kopf, M. Schlüter, D. Kaufhold, L. Hilterhaus, A. Liese, C. Wolff, S. Beutel, T. Scheper
    Laminares Mischen in Miniatur-Hohlfasermembranreaktoren durch Ausnutzung von Sekundärströmungen (Teil 1)
    Chemie Ingenieur Technik 83 (7) (2011) 1066-1073, DOI: 10.1002/cite.201100044
  • R. Yuryev, S. Strompen, A. Liese
    Coupled (chemo)enzymatic reactions in continuous flow
    Beilstein Journal of Organic Chemistry, 7 (2011) 1449-1469
  • J. Müller, S. Baum, L. Hilterhaus, M. Eckstein, O. Thum, A. Liese
    Simultaneous determination of mono-, di- and triglycerides in multiphase systems by online FT-IR spectroscropy
    Analytical Chemistry 83 (24) (2011) 9321-9327

2010

  • A. Prediger, A. Bluma, T. Höpfner, P. Lindner, S. Beutel, J. J. Müller, L. Hilterhaus, A. Liese, T. Scheper
    In-situ Mikroskopie zur online-Überwachung von Enzymträgern und Zweiphasenprozessen
    Chemie Ingenieur Technik,  DOI: 10.1002/cite.201000203
  • M. Berheide, S. Peper, S. Kara, W. Sing Long, S. Schenkel, B. Niemeyer, M. Pohl, A. Liese

    Influence of the Hydrostatic Pressure and pH on the Asymmetric 2--Hydroxyketone Formation Catalyzed by Pseudomonas putida Benzoylformate Decarboxylase and Variants thereof
    Biotechnology & Bioengineering 106 (1) (2010) 18-26

2009

2008

2007

  • L. Hilterhaus, A. Liese
    Building blocks
    Advances in Biochemical Engineering/Biotechnology, 105 (2007) 133-173

2006

2005

  • P. Christophliemk, M. Liauw, A. Liese 
    Trendbericht Technische Chemie 2004
    Nachrichten aus der Chemie, 3 (2005) 312-316

2004

2003

  • D. Vasic-Racki, U. Kragl, A. Liese 
    Benefits of enzyme kinetics modelling
    Chemical and Biochemical Engineering Quarterly 17 (1) (2003) 7-118

2002

  • A. Buchholz, L. Greiner, C. Hoh, A. Liese 
    Genetic algorithms as tool for capillary electrophoresis method development
    Journal of Capillary Electrophoresis and Microchip Technology 7(3 & 4) (2002) 51-60

2001

  • S. Laue, L. Greiner, J. Wöltinger, A. Liese

    Continuous application of chemzymes in a membrane reactor: Asymmetric transfer hydrogenation of acetophenone
    Advanced Synthesis & Catalysis 343 (6-7) (2001) 711-720
    DOI: 10.1002/1615-4169(200108)343:6/7<711::AID-ADSC711>3.0.CO;2-1

  • C. Hoh, G. Dudziak, A. Liese (2001)

    Optimization of enzymatic synthesis of O-glycan core 2 structure by use of a genetic algorithm
    Bioorganic & Medicinal Chemistry Letters 12 (7), 1031-1034

  • N. Bézay, G. Dudziak, A. Liese, H. Kunz (2001)
    Chemoenzymatisch-chemische Synthese eines (2-3)-Sialyl-T-Threonin-Bausteins und dessen Einsatz in der Synthese der N-terminalen Sequenz von Leukämie-assoziierten Leikosialin (CD34) 
    Angewandte Chemie 113 (12), 2350-2352 
    Angewandte Chemie Int. Ed. 40, 2292-2295

    DOI: 10.1002/1521-3757(20010618)113:12<2350::AID-ANGE2350>3.0.CO;2-R

2000

  • C. Wandrey, A. Liese, D. Kihumbu (2000)
    Industrial biocatalysis: Past, present and future
    Organic Process Research & Development 4, 286-290

  • G. Dudziak, N. Bézay, T. Schwientek, H. Clausen, H. Kunz, A. Liese (2000)
    Cyclodextrin- assisted glycan chain extension on a protected glycosyl amino acid
    Tetrahedron 56 (32), 5865-5869

  • H. Iding, P. Siegert, T. Dünnwald, M. Müller, L. Greiner, A. Liese, J. Grötzinger, A. Demir, M. Pohl (2000)
    Benzoylformate decarboxylase from Pseudomonas putida as stable catalyst for the synthesis of chiral 2-hydroxy ketones
    Chemistry - a European Journal 6 (8), 1483-1495

    DOI: 10.1002/(SICI)1521-3765(20000417)6:8<1483::AID-CHEM1483>3.0.CO;2-S

1999

  • A. Liese, M. Karutz, J. Kamphuis, C. Wandrey, U. Kragl (1996)
    Enzymatic resolution of 1-phenyl-1,2-ethanediol by enantioselective oxidation: Overcoming product inhibition by continuous extraction
    Biotechnology and Bioengineering 51, 544-550

    DOI: 10.1002/(SICI)1097-0290(19960905)51:5<544::AID-BIT6>3.0.CO;2-C

Other publications

  • L. Hilterhaus, J. Müller, A. Liese, M. Eckstein, O. Thum

    Kleine Gasblasen, große Wirkung
    Labor & More, 04/09, S. 12-14

  • A. Liese
    Industrielle Biotechnologie
    INGENIEUR-NACHRICHTEN 3/2007, S. 6
  • A. Liese, L. Hilterhaus
    Mehrstufenenzymprozesse
    Labor&More 01/07, S. 68-69
  • T. Becker, A. Liese, T. Maskow, A. Schippers, R. Takors, R. Ulber (2004)

    Biotechnologie ganz groß - In: Biotechnologie 2020 - Von der gläsernen Zelle zum maßgeschneiderten Prozess
    DECHEMA Broschüre des Zukunftsforums

Books

  • J. Tao, G.-Q. Lin, A. Liese
    Biocatalysis for the Pharmaceutical Industry
    Wiley-VCH, 2009, 1st edition, ISBN 
    0-470-82314-3

     


     

  • A. Liese, K. Seelbach, C. Wandrey

    Industrial Biotransformations
    Wiley-VCH, 2006, 2nd edition, 556 S., ISBN 3-527-31001-0

     

  • Industrial Biotransformations (Chinese ed.)

    2005, 1st edition

  • A. Liese

    Biological Principles Applied to Technical Asymmetric Catalysis
    Verlag Forschungszentrum Jülich, 2003, 207 S., ISBN 3-89336-344-0

     

  • A. Liese, K. Seelbach, C. Wandrey

    Industrial Biotransformations                                  
    Wiley-VCH, 2000, 1st edition, 423 S., ISBN 3-527-30094-5


Book chapters

  • L. Hilterhaus, A. Liese

    Industrial Application and Processes Forming C-O Bonds
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • R. Yuryev, L. Hilterhaus, A. Liese

    Industrial Applications and Processes Using Enzymes Acting on C-N Bonds
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese

    Industrial Application and Processes Using Carbon-Carbon Lyases
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • K. Götz, L. Hilterhaus, A. Liese

    Industrial Application of Oxidoreductase catalyzed Reduction of Ketones and Aldehydes
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese

    Industrial Application and Processes Using Biocatalysts for Oxidation Reactions
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • L. Hilterhaus, A. Liese

    Industrial Application and Processes Using Isomerases
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012)
  • A. van den Wittenboer, L. Hilterhaus, A. Liese

    Industrial Applications of Enzymes in Emerging Areas
    In: Enzyme Catalysis in Organic Synthesis, K. Drauz, H. Gröger, O. May (Ed.), 3rd edition, Vol. 1, 2, 3
    Wiley-VCH (2012).
  • L. Hilterhaus, A. Liese

    Bioprocess Development
    In: Manual of Industrial Microbiology and Biotechnology 3rd edition (Zhao, sect. ed.)
    (2008) ASM Press

  • L. Hilterhaus, A. Liese

    Applications of reaction engineering to industrial biotransformations 
    In: Biocatalysis for the Pharmaceutical Industry (Tao, Lin, Liese eds.)
    Wiley (2009), 65-88
    ISBN 0-470-82314-3 

  • U. Kragl, A. Liese

    Reaction on immobilized biocatalysts
    in Handbook of Heterogeneous Catalysis, 2nd Edition, Wiley-VCH, (2008)

  • L. Greiner, S. Laue, J. Wöltinger, A. Liese
    Continuous Asymmetric Hydrogenation 
    in Topics in Current Chemistry: In Situ NMR Methods in Catalysis (Bargon, Kuhn), Springer-Verlag Berlin Heidelberg 2007, 111-124
  • M. Pohl, A. Liese
    Industrial processes using lyases for C-C, C-N, and C-O-bond formation 
    in Patel: Biocatalysts in the Pharmaceutical and Biotechnology Industries (2007), 661-676
    CRC-Press, edited by R. Patel
  • S. Lütz, U. Kragl, A. Liese, C. Wandrey
    Reaction engineering in asymmetric synthesis 
    in Asymmetric Synthesis with Chemical and Biological Methods (Enders, Jaeger), Wiley- VCH (2007), 415-427

  • R. Ulber, A. Liese, D. Sell, E. Flaschel

    Entwicklung der Weissen Biotechnologie in der deutschen Hochschullandschaft in Kooperation mit der Industrie 
    in Fachbuch Weiße Biotechnologie, DBU, BIOCOM AG (2006) 67-75

  • S. Briechle, A. Liese, M. Howaldt, T. Roethig

    Enzymatische Prozesse 
    in Bioprozesstechnik (Chmiel, ed.), Elsevier (2006), 361-408

  • L. Hilterhaus, A. Liese, M. Howaldt, H. Chmiel
    Enzymkinetik 
    in Bioprozesstechnik (Chmiel, ed.), Elsevier (2006), 67-97
  • L. Greiner, A. Liese
    Hydrogenation and other reduction reactions 
    in Multiphase Homogeneous Catalysis 
    (Cornils, Herrmann, Vogt, Horvarth, Olivier-Bourbigou, Leitner, Mecking, eds), Wiley-VCH (2005), 819-834

  • B. Lingen, A. Liese, M. Müller (2003)
    Enantioselective synthesis of hydroxy ketones via benzaldehyde lyase- and benzoylformate decarboxylase-catalyzed C-C bond formation
    in Thiamine: Catalytic Mechanisms and Role in Normal and Disease States (M. S. Pate and F. Jordan, eds.) Marcel Dekker, New York (in press)
  • N. Rao, A. Liese (2003)
    Stereoselective synthesis with the help of recombinant enzymes
    in Molecular Biology in Medicinal Chemistry (Dingermann, Folkers, Steinhilber, eds.; 
    Series: Methods and Principles in Medicinal Chemistry, series editors: K. Mannhold, H. Kubinyi, G. Folkers; Wiley-VCH, 125-152
  • A. Liese (2003)
    53 Keywords in Catalysis from A to Z
    (Cornils, Hermann, Schlögl, Wong, eds.) Wiley-VCH
  • A. Liese, S. Lütz (2002)
    Relevanz der Elektrochemie in oxidativen Biotransformationen
    GDCh Monographie der Fachgruppe Angewandte Elektrochemie: Elektronentransfer in Chemie und Biochemie
    (J. Russow, H.J. Schäfer) 23, 305-308
  • A. Liese (2002)
    Replacing chemical steps by biotransformations: Industrial application and processes using biocatalysis
    in Enzyme Catalysis in Organic Synthesis, 2nd edition, (K. Drauz, H. Waldmann, eds.), VCH-Wiley, 1419-1460

  • U. Kragl, A. Liese (1999)
    Biotransformations, engineering aspects
    in: The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis & Bioseparation, eds. M. C. Flickinger and S. W. Drew, John Wiley & Sons, New York, 454-464

Patents

  • J. Beliczey, U. Kragl, A. Liese, C. Wandrey, H. Coenen, K. Hamacher and T. Tierling 
    Enzymatic synthesis of 3-fluoroneuraminic acid (5-acetamido-3,5-didesoxy-3-fluoro-D- glycero-D-galacto-nonulopyranosonic acid) and other 3,5-didesoxy-3-fluorononulopyranosonic acid derivatives
    US 6,355,453 B1 (12.03.2002, patent application: US 09/156322, 18.09.1998)
  • S. Laue, A. Liese, C. Wandrey, O. Burkhardt, J. Woeltinger, A. Bommarius, H. Henniges, J.-L. Philippe, A. Karau, K. Drauz 
    Use of molecular weight-enlarged catalysts in a process for assymetric, continuous hydrogenation, novel molecular weight-enlarged ligands and catalysts
    US 6,759,559 B1 (6.07.2004)
  • T. Stillger, M. Villela, A. Liese, C. Wandrey
    Verfahren und Vorrichtung zur enzymatischen Co-Faktoren-Regenerierung
    PT 1.1861 DE 100 60 602 (29.07.2005)

Patent applications

  • A. Liese, P. Bubenheim, K. Suck, U. Sohling, F. Ruf

    Verfahren zur Auftrennung von Alkohol-Keton-Gemischen
    DE 102009032080.6-43, 2009

  • O. Thum, L. Hilterhaus, A. Liese
    Verfahren zur enzymatischen Herstellung von Carbonsäureestern
    German patent application 102008004726.0, DE 2008P00002, 28.01.2008
  • O. Thum, L. Hilterhaus, A. Liese
    Verfahren zur heterogenkatalysierten Herstellung von Carbonsäurederivaten
    German patent application 102008004725.2, DE 2008P00003, 28.01.2008
  • M. de Oliviera Villela Filho, W. Hummel, C. Wandrey, A. Liese
    Verfahren zu Herstellung von Alkoholen aus Substraten mittels Oxidoreduktasen, Zweiphasensystem umfassend eine wässrige Phase und eine organische Phase sowie Vorrichtung zur Durchführung des Verfahrens
    DE 102 08 007.0 (26.02.2002, German patent application)
  • A. Brommarius, H.-P. Krimmer, D. Reichert, J. Almena, A. Karau, J. Wöltinger, K. Drauz, A. Liese, L. Greiner, C. Wandrey
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    EP 011 20 796.6 (11.09.2001, European patent application)
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    DE 101 39 958.8 (21.08.2001, German patent application)
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Liese

News

New PhD position at ITB. Topic: Experimental and theoretical processing of biocatalytic cascade reactions.

New PhD position at ITB.

Topic: Experimental and theoretical processing of biocatalytic cascade reactions.

Complete offer information available here.

Edgar Gamero joins the ITB for his Master Thesis. Welcome!

Edgar Gamero joins the ITB for his Master Thesis. Welcome!

Edgar will work in the topic "Etablierung einer Hochzelldichtefermentation und eines Aktivitätstest zur Oxidation von Alkanen".

Good luck and welcome!

Dr. Martina Schedler has succesfully completed her PhD!

Martina Schedler has succesfully completed her PhD "Microbial degradation of crude oil at high pressure".

Congratulations!!

Aparna Nair joins the ITB for her Master's Project Work. Welcome!
Aparna Nair joins the ITB for her Master's Project Work. Welcome!

Aparna will work in the topic "Optimization of crude oil fractionation procedures for biodegradation analysis at high pressure conditions".

Good luck and welcome!